Personal pages menu

Krista Kostial-Šimonović

Krista Kostial-Šimonović, Fellow of the Croatian Academy of Sciences and Arts

Date of birth:

  • 12/19/1923

Place of birth:

  • Osijek

Addresses:

  • Address: Ksaverska c. 2, P.O. Box 291, 10000 Zagreb

E-mails:

Academic titles:

  • Fellow of the Croatian Academy of Sciences and Arts
  • Doctor of Science

Institutions:

  • Znanstvena savjetnica u miru - Institute for Medical Research and Occupational Health

Membership in Academy:

  • Full member - The Department of Natural Sciences (07/24/1991 - ...)
  • Extraordinary member - The Department of Natural Sciences (06/04/1981 - 07/24/1991)

DATE AND PLACE OF BIRTH: December 19, 1923, Osijek, Croatia

EDUCATION:

1943-1949
Study of Medicine, Medical School, University of Zagreb

1949-1951
Postgraduate Study of Occupational Health, University of Zagreb

1951-1952
Department of Physiology, Medical School, University of Zagreb

1952-1953
Department of Physiology, University College, London, UK

Honorary Research Assistant (WHO fellowship)

1960-1961
Radiobiological Research Unit, MRC, Harwell, UK (IAEA fellowship)

DEGREES:

1949
M.D., Medical School, University of Zagreb

1955
Ph.D. in Medical Sciences, University of Zagreb

1956
Habilitation in Physiology (Venia legendi), Medical School, University of Zagreb

1963
Professorship (adjunct appointment) at Faculty of Natural Sciences, University of Zagreb

EMPLOYMENT:

1950-1989
Institute for Medical Research and Occupational Health, Zagreb

1950
Research Assistant

1956-1964
Higher Research Assistant;
Head Department of Toxicology;

Head Department of Biophysics

1964-1989
Scientific Consultant;
Head of the Laboratory for the Physiology of Mineral Metabolism;

Deputy Director

From 1981
Member of the Croatian Academy of Sciences and Arts

RESEARCH ACTIVITIES:

Research Field: Physiology and Toxicology

Research topic: Mineral Metabolism

Participation in national research projects after retirement:

1-03-138 "Metals in the Environment and Their Health Impact" (1991-1994)

00220102 "Metals: Exposure, Effects and Antidotes" (from 1996, in progress)

Publishing activity: ca. 280 original papers in scientific journals, books and congress proceedings (see the List of Publications); ca. 1500 citations in Science Citation Index

TEACHING ACTIVITY:

Postgraduate courses in Mineral Metabolism at Postgraduate study of Natural Sciences, University of Zagreb, scientific field Biology - Physiology and Imunobiology (former Biomedicine) from1960.

Mentorship of twenty M.Sc. and nineteen Ph.D. degrees at the Faculty of Medicine and Faculty of Natural Sciences, University of Zagreb.

SCIENTIFIC SOCIETIES, EDITORIAL BOARDS AND OTHERS:

Member of the Physiological Society (London); American Nuclear Society; Society of Human Biologists; and a number of local scientific societies

Honorary Member of the Hamdard Foundation, Karachi, Pakistan

Member of the Executive Boards of the journals: Arhiv za higijenu rada i toksikologiju, Journal of Applied Toxicology, Advances in Biosiences

Included in international registers of outstanding people in 20th century: Marquis Who's Who in the World (New Providence, NJ, USA), International Biographical Centre (Cambridge, UK) etc.

AWARDS AND RECOGNITIONS:

Decoration for advancement of science, 1965
"Rudjer Boškovic Award", Republic of Croatia, 1969
Award by United States Environmental Protection Agency and National Institutes of Health - Agriculture Research Service, USA, for results achieved on joint research projects, 1979
Award by the Institute for Medical Research and Occupational Health, 1988
Award by the University of Zagreb on 320th "Dies Academicus" anniversary, 1989
Award for Life Achievement, 1994
"Order of the Croatian Morning Star with the Figure of Ruder Boškovic" for the contribution to science decorated by the President of the Republic of Croatia, 1996

OTHER ACTIVITIES (see APPENDIX)

1966
Participation in preparing seven international documents
(WHO; US EPA; US DOE; IPCS, CEC; IAEA; FAO)

1978-1989
Consultant to scientific organizations 11 times (WHO; CEC; IAEA)

1961-1988
Principal investigator on nine international research projects
(IAEA, CEC; US EPA; NIH)

1977-1990
Invited speaker at international conferences 21 times

1979-1991
Invited papers - international editions (19)

1986, 1991
Invited review articles (3)

APPENDIX

International documents
Consultant to international scientific organizations
International research projects (principal investigator)
Invited speaker (international conferences)
Invited papers (international editions)
Invited review articles (international editions)
International documents

1982. Lead Air Quality Criteria Document, US Environmental Protection Agency (document's referee)
1983. Health Assessment Document for Manganese, US Environmental Protection Agency (participated in preparing the part of the document related to metabolism)
1992. Environmental Health Criteria 59. Principles for Evaluating Health Risks from Chemicals during Infancy and Early Childhood: The Special Need for a Special Approach. International Programme on Chemical Safety, Commission of the European Communities, World Health Organization (engaged in preparing the whole document)
1992. Environmental Health 32. Heavy Metal and PAH Compounds from Municipal Incinerators. World Health Organization - Regional Office for Europe, Copenhagen (participated in preparing the part of the document related to metals)
1992. IAEA-TEC DOC "Significance of Hair Mineral Analysis as a Means for Assessing Body Burdens of Environmental Mineral Pollutants" (participated in part of the document related to animal studies)
1993. WHO/FAO/IAEA "Trace Elements" (author of Chapter related to influence of physiological and dietary factors on toxicokinetics and toxicity of metals)
1996. US EPA-US DOE "Mercury Speciation Workshop" (reviewer of the Workshop papers)
Consultant to international scientific organizations

1978 - WHO consultant for USA in the field of nutrition and toxicity of metals, Washington, DC
1983 - CEC and WHO consultant at the meeting of experts "Principles for Evaluating Health Risks from Chemicals during Infancy and Childhood", Cambridge, UK (co-chairman)
1983 - IAEA consultant at the meeting of experts "Handling of Over-Exposed People", Vienna, Austria
1983 - WHO consultant at the meeting "IPCS Workig Group on Lead Risk in Children", Geneva, Switzerland
1984 - IAEA consultant at the meeting "Hair as an Indicator of the Body Burden of Metals", Vienna, Austria (chairman of session)
1984 - CEC and WHO consultant at the meeting "Workshop on the Evaluation of the Health Risks from Chemicals in Infancy and Childhood Including the Assessment of the Toxicity of Chemicals in Human Milk", Luxembourg (co-chairman)
1985 - IAEA consultant at the metting "Significance of Hair Mineral Analysis as a Means for Assessing Internal Body Burdens of Environmental Mineral Pollutants", Neuherberg, Germany
1985 - CEC and WHO consultant at the meeting "Principles for Evaluating Health Risks from Chemicals during Infancy and Childhood", Cambridge, UK (co-chairman)
1987 - WHO consultant at the meeting "Working Group on Health Hazards of Heavy Metals and PAH Compounds from Municipal Waste Incineration", Firence, Italy (co-chairman)
1987 - IAEA consultant at the meeting "Significance of Hair Mineral Analysis as a Means for Assessing Internal Body Burdens of Environmental Mineral Pollutants", Amsterdam, Netherland (co-chairman)
1989 - IAEA consultant at the meeting "The Significance of Hair Mineral Analysis as a Means to Assessing Internal Body Burden of Environmental Pollutants", Neuherberg, Germany (co-chairman)
International research projects

Some Factors Influencig Mammalian Retention of Radioactive Strontium (International Atomic Energy Agency, 1961-1964 - principal investigator)
Studies on Abnormal Lead Absorption, Lead Poisoning and Lead Chelation (National Institute of Health, USA, 1972-1976 - principal investigator in experimental part)
Lead and Peripheral Neuropathy (US Environmental Protection Agency, 1972-1976 - principal investigator in experimental part)
Factors Influencing Lead Absorption from the Intestine (US Environmental Protection Agency, 1972-1976 - principal investigator)
Calcium Metabolism in Relation to Age, Sex and Calcium Intake (US Department of Agriculture, Agricultural Research Service - 1972-1977 - principal investigator)
Effect of Environmental Pollutants in Relation to Age and Dietary Influence. Toxic Trace Elements (US Environmental Protection Agency, 1978-1983 - principal investigator)
Evaluation of the Effect of Lead on Reproduction. Animal Study to Evaluate the Effect of Lead on Reproduction Following Male and Female Exposure to Lead (Commission of the European Communities, 1983-1984 - principal investigator)
Significance of Hair Mineral Analysis as a Means for Assessing Body Burdens of Environmental Mineral Pollutants: Influence of Age (International Atomic Energy Agency, 1983-1988 - principal investigator)
Delayed Effect of Lead on Kidney Function and Structure (US Environmental Protection Agency, 1984-1985 - principal investigator in experimental part)
Invited speaker (international conferences)

1977 Meeting on Factors Influencing Metabolism and Toxicity of Metals, Stockholm, Sweden (Karolinska Institute and WHO)
1977 71st Annual Meeting APCA, Houston, Texas, USA (invitation of the organizers)
1978 International Conference on Cadmium, National Institutes of Health, Bethesda, USA (National Institutes of Health)
1979 YU-USA Seminar "Effects of Industrial Pollution on the Environment", University of Prishtina and Fullbright Commission. Prishtina, former Yugoslavia (Fullbright Foundation)
1979 Symposium on Metal Toxicities, Nutrition Society, Great Britain, Aberdeen, Great Britain (Royal Academy)
1980 International Symposium "Lead in the Marine Environment", Rovinj (by invitation of the organizers)
1981 Symposium on the Health Evaluation of Heavy Metals in Infant Formula and Junior Food, Berlin, Germany (Ministry of Health, Germany)
1982 15th Annual Conference on Reproductive and Developmental Toxicology of Metals, Rochester, USA (University of Rochester and National Institute of Health)
1982 Metallothionein and Cadmium Nephrotoxicity Conference, Research Triangle Park, USA (National Institute of Health)
1983 International Symposium on Elements in Health and Disease, Karachi, Pakistan (Hamdard Foundation)
1985. Second NAS-SAJ Joint Workshop "Selected Aspects of Exposure to Heavy Metals in the Environment, Monitor, Indicators and High Risk Groups", Washington 1985 (National Academy of Sciences, USA)
1985 Seminar "Speciation of Fission and Activation Products in the Environment", Oxford, England (Commission of the European Communities and National Radiological Protection Board, England)
1986 XVIII International Congress of Pediatrics, Honolulu, Hawaii, USA (by invitation of the organizers)
1988 International Symposium on Chemical Mixtures: Risk Assessment and Management, Cincinnati, USA (US Environmental Protection Agency)
1989 International Conference on Elements in Health and Disease, Karachi, Pakistan (Hamdard Foundation)
1989 Consultation on Genetic Predisposition to Toxic Effects of Chemicals, Krefeld, Germany (WHO)
1989 Third International Congress on Trace Elements in Health and Disease, Adana, Turkey (by invitation of the organizers)
1990 Seventh International Symposium on Trace Elements in Man and Animals (TEMA-7), Dubrovnik (Parent Committee TEMA)
1990 Teisinger's Days, Prague, Czech Republic (Institute of Industrial Hygiene)
1990 Symposium on Advances in Mercury Toxicology, Tokyo (National Science Foundation, USA and Japanese Society for Promotion of Science)
1990 Chemical Speciation and Bioavailability, Chapel Hill, North Carolina, USA (US Environmental Protection Agency)
Invited papers (international editions)

Kostial K, Jugo S, Rabar I, Maljkovic T (1979). The influence of age on metal metabolism and toxicity. Environ Health Perspect 25:81-86
Kostial K, Kello D, Blanuša M, Maljkovic T, Rabar I (1979). Influence of some factors on cadmium pharmacokinetics and toxicity. Environ Health Perspect 28:89-95
Kostial K, Rabar I, Blanuša M, Landeka M (1979). Influence of age on heavy metal absorption. Proc Nutr Soc 38:251-256
Kostial K, Kello D, Blanuša M, Maljkovic T, Rabar I, Bunarevic A, Stara JF (1980). Toxicologic studies of emissions from coal gasification process. I. Subchronic feeding studies. J Environ Pathol Toxicol 3:437-448
Kostial K (1980). Some factors influencing lead metabolism. In: Lead in the Marine Environment (M. Branica, Z. Konrad, eds.), Pergamon Press, pp. 271-277
Kostial K (1982). The absorption of heavy metals by the growing organism: experimental experience with animals. In: Health Evaluation of Heavy Metals in Infant Formula and Junior Food (E.H.F. Schmidt, A. Hildebrandt, eds.), Springer Verlag Berlin, pp. 99-104
Kostial K (1983). Specific features of metal absorption in suckling animals. In: Reproductive and Developmental Toxicity of Metals (T.W. Clarkson, G.F. Nordberg, P.R. Sager, eds.), Plenum Press New York, pp. 727-744
Kostial K (1987). Age as a factor influencing metal metabolism. In: Selected Aspects of Exposure to Heavy Metals in the Environment. Monitors, Indicators and High Risk Groups. Summary Proceedings of a Workshop. National Academy of Sciences USA and Council of Academies and Arts Yugoslavia. Washington, DC 1985. National Academy Press. Washington, DC 1987. pp. 28-35
Kostial K (1984). Effect of age and diet on renal cadmium retention in rats. Environ Health Perspect 54:51-56
Kostial K (1984). Age as a factor in element metabolism and toxicity. Proceedings of the First International Conference on Elements in Health and Disease (S.B. Vohora, M.S.Y. Khan, eds.), New Delhi 1984. Institute of History of Medicine and Medical Research. New Delhi 1984. pp. 246-254
Kargacin B, Kostial K (1986). Uptake of radionuclides from the gastrointestinal tract in rats fed different food. In: Speciation-85 Seminar "Speciation of Fission and Activation Products in the Environment" (R.A. Bulman, J.R. Copper, eds.), Elsevier Applied Science Publishers London - New York, pp. 184-190
Kostial K, Blanuša M, Maljkovi T, Kello D, Rabar I, Stara JF (1989). Effect of a metal mixture in diet on the toxicokinetics and toxicity of cadmium, mercury and manganese in rats. Toxicol Ind Health 5:685-698.
Kostial K, Blanuša M, Karga in B, Landeka M (1989). Effect of age, sex and chelating agents on the retention of metals in hair of rats. In: Elements in Health and Disease (M. Said, M.A. Rahman, L.A. D'Silva, eds.), Proceedings of 2nd International Conference, Karachi: Hamdard University Press, pp. 331-342.
Kostial K, Blanuša M, Maljkovic T, Kargacin B, Piasek M, Momcilovic B (1991). Age and sex influence the metabolism and toxicity of metals. In: Trace Elements in Man and Animals - 7. Proceedings of the Seventh International Symposium on Trace Elements in Man and Animals TEMA-7 (B. Momcilovic , ed.), Dubrovnik 1990. Zagreb: Institute for Medical Research and Occupational Health University of Zagreb. pp. 11/1-5.
Kostial K, Kargacin B, Landeka M (1991). Efficiency of chelation therapy in relation to age. In: Trace '89. Proceedings of the Third International Congress on Trace Elements in Health and Disease (G.T. Yuregir, O. Donma, L. Kayrin, eds.), Adana, Turkey 1989. Adana: Cukurova University Publishing Company, pp. 135-144.
Kostial K, Kargacin B, Arezina R, Landeka M, Šimonovic I (1991). Factors influencing the efficiency of chelation therapy. J Hyg Epidemiol Microbiol Immunol 35:337-350.
Blanuša M, Kostial K (1991). Dietary exposure to lead and cadmium in Yugoslavia. Chemical Speciation and Bioavailability 3:17-20.
Kostial K, Blanuša M, Kargacin B, Piasek M, Maljkovic T, Kello D (1991). Sex-related differences in genetic susceptibility to toxic metals. In: Ecogenetics: Genetic Predisposition to the Toxic Effects of Chemicals (E.C. Grandjean, ed.), WHO Regional Office for Europe, Copenhagen, Denmark. Chapman & Hall London, pp. 111-122.
Kargacin B, Kostial K (1991). Methods for decreasing Hg-203 retention in relation to age and route of exposure. In: Advances in Mercury Toxicology (T. Suzuki, N. Imura, T.W. Clarkson, eds.), Plenum Press New York, pp. 135-155
Invited review articles (international editions)

Kostial K (1986). Cadmium. In: Trace Elements in Human and Animal Nutrition. Vol. II, 7th Edition (W. Mertz, ed.), Academic Press New York, pp. 319-345.
Kargacin B, Kostial K (1991). Toxic Metals: Influence of Macromolecular Dietary Components on Metabolism and Toxicity. Chapter 7. In: Nutrition, Toxicity, and Cancer (I.R. Rowland, ed.), CRC Press Inc., Boca Raton, FL, pp. 197-221

Louis Vuitton Bags Doudoune Moncler Moncler Outlet louis vuitton outlet Louboutin Pas Cher Louis Vuitton Soldes Moncler Jackets Louis Vuitton Borse Gucci Borse Moncler Soldes Louis Vuitton Outlet Louis Vuitton Sac Louis Vuitton Outlet Gucci Outlet Moncler Pas Cher Cheap Moncler Jackets cheap jerseys Louis Vuitton Pas Cher Moncler Doudoune Louis Vuitton Handbags Louboutin Chaussures Louis Vuitton Outlet cheap ugg boots outlet Louis Vuitton Outlet moncler jackets outlet MCM Outlet